Live C-Suite Conversations on AI

CIO Survival: Lessons from AI Early Adopters in the Enterprise

In CXOTalk episode 869, discover actionable strategies for aligning AI innovation with business objectives with two world-leading CIO advisors. Explore the pitfalls and lessons learned!

CIO Survival: Lessons from AI Early Adopters in the Enterprise

56:07

Recently Added

Jul 17, 2026 |

Agentic AI in Financial Services: Former UBS and SAP Group CIO

Banks run dozens of AI pilots, but almost no AI agents in production, and the gap is in controls, not models. Former UBS Group CIO Oliver Bussmann outlines the key conditions that must be met before agents can go live.

Jul 17, 2026

Jul 10, 2026 |

IBM Consulting: The CIO Agenda for AI

AI is moving from pilot projects to the center of how large companies operate, and CIOs own the transition. IBM Consulting's Andy Baldwin shares practical advice for the next 12 months.

Jul 10, 2026
54:18

Jun 26, 2026 |

Can You Build an Incorruptible AI Company? A Conversation with Eric Ries

Most companies, including AI startups, lose their way as they grow, trading their founding mission for short-term profit, says Eric Ries, author of The Lean Startup. He explains why this corruption happens and shares the governance structures that keep a company loyal to its purpose.

Jun 26, 2026
53:35

Jun 19, 2026 |

McKinsey on Agentic AI: How to Create Business Value

Although companies spend heavily on AI, few capture its value, according to McKinsey QuantumBlack. Their global leader explains why and shares a repeatable process for enterprise and agentic AI.

Jun 19, 2026
53:35

Jun 12, 2026 |

Box CEO Aaron Levie: CIO Advice on Agentic AI and the Enterprise

Box CEO Aaron Levie joins CXOTalk episode 921 to explain why enterprise AI agents stall in production, how they break existing security models, and what CIOs should fix first.

Jun 12, 2026
57:02

May 29, 2026 |

Mozilla CTO: Open Source AI Agents and the Fight for Control

AI agents have become essential enterprise tools. The platforms companies choose now will decide whether they own their AI or depend on big tech. Mozilla CTO Raffi Krikorian argues that open-source AI agents are the key to real independence.Key points:AI agents act inside your systems, and most enterprises have limited visibility into whose interests they serveBuilding on closed, proprietary platforms means the vendor controls your agent's behavior, data access, and roadmapKrikorian explains the open-source alternative and what enterprise control of AI actually requires 

May 29, 2026
42:15

May 15, 2026 |

CIO Playbook: Agentic AI in the Enterprise

Agentic AI is changing what CIOs are accountable for. Systems that plan, act, and call tools on their own now operate within workflows the CIO no longer fully owns, while boards expect the same standards of security, risk management, and business value. CXOtalk episode 919 turns that pressure into a practical playbook for leading agentic AI in the enterprise.Key points:The CIO mandate shifts from running systems to governing autonomy, with clear decision rights, agent boundaries, and accountability.Trust, data, and control must be managed together, especially when the middle layer of models, agents, and vendors is opaque, and shadow AI is already inside the business.Human oversight must be designed for machine speed, with explicit roles before, during, and after AI operates, backed by an operating model and culture built for continuous change.

May 15, 2026
18:03

May 05, 2026 |

Autonomous Software Development at Enterprise Scale: Inside a 1,000-Developer Pilot (with Blitzy)

AI-driven autonomous software development is transitioning from pilot projects to real production deployments in 2026. CIOs managing large developer teams must decide which tasks to delegate to agentic platforms and the speed of this transition. CXOTalk episode 918 examines how Mexico's largest insurer made those decisions, including pilot design, measured velocity gains, changes to the developer role, and the governance inputs required to keep autonomous output aligned with enterprise compliance standards.Key PointsTest Autonomy Across Mixed Use Cases First. GNP structured their pilot around four concrete scenarios: backend language upgrade, frontend framework migration, new feature builds, and security vulnerability remediation, using live repository and CI/CD connections.Move Guardrails into the Prompt Layer. Treat technical standards, security policies, and test requirements as prompt inputs alongside functional specifications, so the platform produces code that meets corporate guidelines by design.Redefine Developer Roles Around Direction, Not Code. Shift engineers from line-by-line coding into prompt authorship, architecture review, and validation of autonomous output, with co-pilots handling any residual work.

May 05, 2026

Upcoming Episodes

Friday, 31 July
1:00 PM EDT

Interview and Conversation with Nate B. Jones, AI Analyst and Advisor

Nate Jones

AI Analyst and Advisor

Friday, 7 August
1:00 PM EDT

Ed Sim, Founder and General Partner, Boldstart Ventures

Ed Sim

Founder and General Partner

Boldstart Ventures

Friday, 28 August
1:00 PM EDT

Interview and Conversation with Tamar Yehoshua, Chief Product and AI Officer, Atlassian

Tamar Yehoshua

Chief Product and AI Officer

Atlassian